School of Biotechnology

Madurai Kamaraj University, Madurai

Research Interests

Molecular Modelling and Docking

• Prediction and molecular modeling of 3D structure of a protein drug target from its sequence

• Docking of ligand molecule to its receptor molecule and Identification of hostspots for ligand binding

Comparative genome sequence analysis

It is highly interesting to study the relationship of genome structure and function between two organisms that may give meaningful information about the function and evolutionary processes that act on genomes. The purpose is to gain a better understanding of how species have evolved and to determine the function of genes

Pharmacogenomics

Pharmacogenetics deals with inherited differences in the response to drugs. Pharmacogenomics is the whole genome application of pharmacogenetics, which examines the single gene interactions with drugs. Hence, pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Such approaches promise the advent of "personalized medicine"; in which drugs and drug combinations are optimized for each individual's unique genetic makeup