School of Biotechnology

Madurai Kamaraj University, Madurai

Research Programmes

The major research areas of the School of Biotechnology where active work is in progress are

Research Projects :

Some of the major research projects completed/ ongoing in the School are listed below

Completed  

S.No

Project Title

Funding Agency

Period

Outlay

Principal Investigator

1.

Genetic Instability in Streptomyces

D.A.E, Bombay

1992 � 1996

8.15 Lakhs

K.Dharmalingam

2.

Molecular analysis of anthracycline production in Streptomyces

DBT

1992 - 1998

28.66 Lakhs

K.Dharmalingam

3.

Purification and crystallisation of the restriction endonuclease McrA from E.Coli

DST

1992-1995

6 Lakhs

S.Krishnaswamy

4.

Biological control of pests of tea using Bacillus thuringiensis

Parry-Agro Industries

Chennai

1993 � 1995

4.50 Lakhs

V.Sekar

5.

Pilot-scale production of a transgenic insecticidal cotton leaf colonizing bacterium

DBT

1994 - 1997

29.5 Lakhs

V.Sekar

6.

Pilot-scale production of a transgenic insecticidal cotton leaf colonizing bacterium

SPIC

1994 - 1998

11.5 Lakhs

V.Sekar

7.

Molecular cloning and characterization of phosphatidyl-D- myoinositol phosphohydrolase

CSIR

1995 - 1998

4.5 Lakhs

V.Sekar

8.

Introduction of the crystal protein gene of Bacillus thuringiensis into non-symbiotic, diazotrophic bacteria of rice

ICAR

1995 - 1999

7.0 Lakhs

V.Sekar

9.

Development of Agrobacterium based transformation system for indica rice

Rockefeller FoundationUSA

1996 - 1997

10 Lakhs

K.Veluthambi

10.

Mechanism of immunosuppresion in leprosy and analysis of M.Leprae genome

Indo-Swiss DBT-ETH Switzerland

1995 � 1999

116.02  Lakhs

K.Dharmalingam

11.

Structural analysis of S.typhi OmpC

DBT

1999 - 2002

16 Lakhs

S.Krishnaswamy

12.

Analysis of the structure function relations of the McrA endonuclease

DBT

1999- 2002

13 Lakhs

S.Krishnaswamy

13.

Understanding structurally the interaction of S.typhi OmpC with the antibodies specific to it

CSIR

1999 � 2002

9 Lakhs

S.Krishnaswamy

14.

Introduction and expression of cry gene(s) of Bacillus thuringiensis in coffee-associated bacteria

DBT/Coffee Board

1999 � 2002

28 Lakhs

V.Sekar

15.

Genetic engineering of indica rice for salinity and drought

Rockefeller FoundationUSA

1999 � 2000

9 Lakhs

A.K.Gupta

16.

Genetic  engineering  of  chillies  for  resistance to chilli leaf curl virus

Rallis-India Ltd

1997 - 2000

12 Lakhs

K.Veluthambi &

R.Usha

17.

Generation of transgenic Vigna mungo plants with yellow mosaic virus resistance by expressing the viral coat protein and  replicase genes

DBT

1999 � 2002

43 Lakhs

K.Veluthambi

18.

Genetic engineering of indica rice for sheath blight resistance

Rockefeller FoundationUSA

1998 � 2000

32 Lakhs

K.Veluthambi

19.

Transformation studies in coffee for fungal resistance using Ti plasmid vectors

DBT

1999 - 2002

23 Lakhs

K.Veluthambi

 

20.

 

Centre for Genetic Engineering and Strain Manipulation

 

DBT

 

1997 - 2002

 

2.12 Crores

 

K.Dharmalingam

21.

Centre for Plant Molecular Biology

 

Genetic Engineering of vigna mungo for yellow mosaic resistance

 

Introduction and expression of cry gene(s) of Bacillus thuringiensis in chloroplasts of crop plants

 

Development of transgenic indica rice with salinity and drought tolerance: Over expression of pyrroline-5-carboxylate synthetase gene

 

Development of transgenic cardamom expressing the coat protein of Indian  cardamom mosaic virus for virus resistance

DBT

1997 -2002

89.1 Lakhs

 

 

 


K.Veluthambi

 

 

V.Sekar

 

 

 


A.K.Gupta


 

 

 

 

R.Usha

22

Evaluation of immunoassay procedure for pesticide analysis

Automic Energy Agency, Austria

1993 - 1999

7 Lakhs

S.R.D.Jebakumar

  

Ongoing

S.No

Project Title

Funding Agency

Period

Outlay

Principal Investigator

1. Engineering of yellow mosaic virus resistance in blackgram (inod Swiss Collaboration in Biotechnology) ISCB Switzerland
DBT New Delhi
Oct. 2004 to
Sep. 2007
   46,44,000/- Dr.K.Veluthambi
2. Functional Genomics on Rice-Gene expression profiling during flower and seed development and functional validation of identified genes DBT New Delhi April 2004 to
March 2009
   53,13,000/- Dr.K.Veluthambi
3. Development of Transgenic Blackgram DBT and Cardamon for virus resistance DBT New Delhi April 2002 to March 2007    57,27,000/- Dr.K.Veluthambi
4. Study of root specific EST�s in tomato DBT, Govt. of India 2005 to
2008
   38,00,000/- Dr.Aditya Kumar Gupta
5. Functional Genomics on Rice-Gene expression profiling during flower and seed development and functional validation of identified genes DBT New Delhi April 2004 to
March 2009
   53,13,000/- Dr.Aditya Kumar Gupta
6. Development of Transgenic Blackgram DBT and Cardamon for virus resistance DBT New Delhi April 2002 to March 2007    57,27,000/- Dr.Aditya Kumar Gupta


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